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Written primarily for students embarking on an undergraduate bioscience degree, this primer introduces students to the essential topics in protein science clearly and concisely by describing the basic chemical structure of proteins, the factors that stabilize protein structures, protein function, and protein evolution. It begins by placing proteins in their general context in life. They are synthesized as amino-acid sequences encoded in genomes, and fold spontaneously to three-dimensional structures. This is the point where life makes the tremendous leap from the one-dimensional world of genome and amino-acid sequences, to the three-dimensional world of protein structures - indeed, the world which we inhabit. Protein Science prepares readers for later more advanced study of the subject, but will also leave readers who do not go on to such advanced study with a satisfying grasp of the essentials of the subject. Protein Science is supported by online resources and is available for students and institutions to purchase in a variety of formats. The e-book offers a mobile experience and convenient access along with functionality tools, navigation features and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks The online resources include: For students: - Self-test questions - Animations of protein structures introduced in the text For registered adopters of the book: * Figures from the book, available to download
Active, accessible, and assuming no prior knowledge: the ideal text for biologists encountering bioinformatics for the first time. A vast amount of biological information about a wide range of species has become available in recent years as technological advances have significantly reduced the time it takes to sequence a genome or determine a novel protein structure. This text describes how bioinformatics can be used as a powerful set of tools for retrieving and analysing this biological data, and how bioinformatics can be applied to a wide range of disciplines such as molecular biology, medicine, biotechnology, forensic science and anthropology. Fully revised and updated, the fifth edition of Introduction to Bioinformatics contains a host of new material including new content on next generation sequencing, function prediction, sequence assembly, epigenomics, the bioinformatics of gene editing, and the effects of single nucleotide variants. Written primarily for a biological audience without a detailed prior knowledge of programming, this book is the perfect introduction to the field of bioinformatics, providing friendly guidance and advice on how to use various methods and techniques. Furthermore, frequent examples, self-test questions, problems, and exercises are incorporated throughout the text to encourage self-directed learning.
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